![]() ![]() Many infectious diseases leading to pandemics are caused by zoonotic pathogens that were transmitted to humans due to increased contacts with animals through breeding, hunting and global trade activities. The world is now facing the new coronavirus disease 2019 (COVID-19) pandemic. Major pandemics and epidemics such as plague, cholera, flu, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) have already afflicted humanity. The emergence and spread of infectious diseases with pandemic potential occurred regularly throughout history. CHU de Québec – Laval University, Quebec City, QC, Canada.or any other plague endemic area and have symptoms suggestive of plague, seek health care immediately. If you live or have recently traveled to the western U.S. Preventive antibiotic therapy may also be given, depending on the type and timing of personal contact. People in close contact with very sick pneumonic plague patients may be evaluated and possibly placed under observation. The earlier a patient seeks medical care and receives treatment that is appropriate for plague, the better their chances are of a full recovery. Plague is a very serious illness, but is treatable with commonly available antibiotics. Once plague has been identified as a possible cause of the illness, appropriate treatment should begin immediately. Diagnosis is made by taking samples from the patient, especially blood or part of a swollen lymph gland, and submitting them for laboratory testing. In many cases, particularly in septicemic and pneumonic plague, there are no obvious signs that indicate plague. A known flea bite or the presence of a bubo may help a doctor to consider plague as a cause of the illness. The most common sign of bubonic plague is the rapid development of a swollen and painful lymph gland called a bubo. Plague is a plausible diagnosis for people who are sick and live in, or have recently traveled to, the western United States or any other plague-endemic area. Doctors examining a bubo caused by plague. ![]()
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